hree general of mosquitoes were fed with HBV-DNA positive humanblood, and bit tupaia belangeri tree shrew The animal models with HBVinfection were obtained. Aften 1 to 2 months, the tupaia belangeri becamethin, hairless and higher mortality due to imporper feeding -nutrition.The dispensations were changed to feed nutrition, according to Nutrientsdesign. The balance pellet feed night increase vitality of Tupaia belangerwith HBV infection.