Hyperuricemia is closely associated with abdominal obesity. The prevalence of hyperuricemia combined with abdominal obesity has been increased significantly in recent years, along with the improvement of daily life and the changes in dietary structure. The state of hyperuricemia combined with abdominal obesity is most harmful, and becomes a common and high risk metabolic disease. Animal model with hyperuricemia combined with abdominal obesity is very important for the research of pathomechanism and treatment of this disease.