Student Brigade of the Forth Battalion, 15th Company, The Fourth Military Medical University, Xian 710032, China;Laboratory Animal Center, The Fourth Military Medical University, Xian 710032, China 在期刊界中查找 在百度中查找 在本站中查找
A class of near infrared fluorescence (NIRF) heptamethine cyanine dyes, in their native form without chemical conjugation, can be taken up and accumulated specifically in cancer cells and used for tumors imaging. The different uptake of the dyes into cancer but not normal cells is possible due to the presence of specific isoforms of organic anion-transporting peptides (OATPs), and regulated by hypoxia. These advances have widely extended current application of NIRF imaging in cancer diagnosis.
