激素性股骨头坏死动物模型的建立及评价
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作者单位:

(1. 甘肃中医药大学, 兰州 730000; 2. 甘肃中医药大学附属医院脊柱外科,兰州 730020)


Establishment and evaluation of animal models of steroid-induced avascular necrosis of the femoral head
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Affiliation:

(1. Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. 2. Department of Spinal Surgery,Affiliated Hospital of Traditional Chinese Medicine University, Lanzhou 730020)

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    摘要:

    由于糖皮质激素的广泛应用,而导致的激素性股骨头坏死的发病率逐年升高,但其发病机制及预防措施仍不明确,为了进行深入研究,从根本上进行治疗,激素性股骨头坏死动物模型的建立将是这些研究成败的关键?本文将造模方案?造模动物以及造模标准的研究进展做一综述?

    Abstract:

    Owing to the widespread use of glucocorticoids, the incidence of steroid-induced avascular necrosis of the femoral head has increased year by year, but its pathogenesis and possible preventive measures are still unclear. To carry out in-depth research into its fundamental treatment, the establishment of an animal model of steroid-induced avascular necrosis of the femoral head will be the key to success. This paper reviews the research progress of modeling schemes, modeling animals and modeling standards.

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蒋玮,曹林忠,邬明峻,张琪.激素性股骨头坏死动物模型的建立及评价[J].中国实验动物学报,2019,27(6):799~804.

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  • 收稿日期:2019-03-31
  • 在线发布日期: 2020-01-07
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