Animal models of hyperuricemia are widely used in relevant research; however, there is currently a lack of standardized preparation and evaluation protocols. Based on a comprehensive review of the domestic and international literature, this article summarizes and analyzes the current applications of hyperuricemia animal models. It systematically categorizes the selection criteria for commonly employed animal models in hyperuricemia studies, with a particular focus on the critical analysis of induced animal modeling method ologies. The findings aim to provide a reference framework for establishing reliable hyperuricemia animal models with enhanced pathophysiological relevance.