Abstract:【Abstract】Objective To classify and analyze the existing animal models of vertigo based on the clinical characteristics of Chinese and Western medicine, evaluate the clinical fit of the models and their advantages and disadvantages, in order to improve the existing animal models and provide a more intuitive reference for clinical research. Methods The existing animal models of vertigo in the database were searched, and the models were classified according to the modeling method, combined with the characteristics of Chinese and Western medicine clinical conditions of vertigo and the existing animal model evaluation methods, and assigned values to evaluate the clinical fit and the advantages and disadvantages of the models. Results The existing animal models of vertigo were neck surgery model, motor stimulation model, otogenic stimulation model, sclerotherapy injection model, flight variation pressure model, vertebral artery ligation model, and stasis injection model; among them, the Western medical fit was high (fit ≥ 60%) for neck surgery model (65%) and otogenic stimulation model (65%), and all models had moderate Chinese medical fit (50% ≤ fit < All models had moderate (50% ≤ 60%) or low (< 50%) TCM anastomosis, and there was no model with both high TCM and WCM anastomosis. Conclusion At present, the animal models of vertigo are mainly Western medicine disease models, and there is a lack of Chinese medicine evidence models, and there are few models with high clinical fit between Chinese and Western medicine, which fail to highlight the characteristics of Chinese medicine. Therefore, the construction of animal models of vertigo that are closely integrated with the clinical characteristics of Chinese and Western medicine can provide more reasonable and comprehensive experimental support for the development, screening and clinical evaluation of new anti-vertigo drugs.