小鼠支气管肺泡灌洗术研究进展
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1.西南医科大学基础医学院;2.西南医科大学附属中医医院

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四川省中医药管理局项目(项目编号:2021XYCZ006);西南医科大学校级科研项目(项目编号:2023XGZX008)


Research progress of bronchoalveolar lavage in mice
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Affiliation:

1.School of Basic Medical Science, Southwest Medical University;2.The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University

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Funded by Project of Sichuan Provincial Administration of Traditional Chinese Medicine (NO. 2021XYCZ006), Project of Southwest Medical University (NO. 2023XGZX008)

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    摘要:

    支气管肺泡灌洗术是研究呼吸系统疾病的一项重要技术,已经在疾病研究中得到广泛运用,目前,临床患者的支气管肺泡灌洗操作流程已经逐步规范化,而小鼠作为研究肺部疾病重要的模型动物之一,尚缺乏针对小鼠的支气管肺泡灌洗液标准采集和检测流程,不规范的流程会阻碍该技术在研究中的推广和应用,同时也会影响实验结果的准确性和可靠性。本文对国内外研究中小鼠支气管肺泡灌洗方法进行了系统的总结,以期为研究者今后运用并建立规范的灌洗流程提供参考和指导。

    Abstract:

    Bronchoalveolar lavage is an important technique for studying respiratory diseases and has been widely used in disease research. Currently, the operation procedure of bronchoalveolar lavage in clinical patients has been gradually standardized, while mice, as one of the important model animals for studying lung diseases, still need a standard collection and testing procedure for bronchoalveolar lavage fluid for mice. An unstandardized procedure can hinder the promotion and application of this technique in research, and also affect the accuracy and reliability of experimental results. This paper presents a systematic summary of bronchoalveolar lavage methods for mice in domestic and international studies, with the aim of providing reference and guidance for researchers to apply and establish a standardized lavage procedure in the future.

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  • 收稿日期:2023-05-18
  • 最后修改日期:2023-09-14
  • 录用日期:2023-09-14
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