Hemophilia Arthritis (HA) is caused by recurrent bleeding, which seriously affects the life of patients and consumes a lot of social and medical resources. Limited by ethical requirements, it is necessary to establish an animal model of HA for research. In order to summarize the research progress of animal models of hemophiliac arthritis, this paper reviewed the literature on animal HA models at home and abroad in recent years, from the aspects of species selection, modeling methods, histopathology, imaging evaluation methods, etc.