The construction of experimental animal models of Chinese medicine syndromes plays an important platform support role in the research of the mechanism of action of Chinese medicine. In recent years, there are more and more reports in the literature on the construction and evaluation of the animal model of spleen deficiency evidence, but there are different standards of the construction method and insufficient objectification of the evaluation indexes. In this paper, we will summarize the construction and evaluation methods of the animal model of spleen deficiency from the aspects of animal selection, model establishment, macroscopic characterization, behavioral experiments, and objective indexes of spleen deficiency. evaluation methods, with a view to providing theoretical guidance for the construction of experimental animal models of spleen deficiency and literature reference for the selection of animal model platforms for spleen deficiency.