Chronic ulcers on the surface of the body are a state of non healing of wounds. Establishing an animal model of chronic wounds similar to humans is an important tool for preventing and understanding the complexity of chronic wound formation and related pathological mechanisms in the human body. Generally speaking, wound animal models are constructed by inducing molecular biology abnormalities through certain external injury interventions to induce wound formation in the body. Common modeling methods include surgical resection, pressure ischemia treatment, drug treatment, radiation treatment, etc. The success of model construction can usually be evaluated by methods such as natural recovery of the wound without intervention, measurement of wound size, observation of physical signs, measurement of body mass, organ index, infrared imaging, etc. Although there are numerous methods for modeling and evaluating animal models of chronic wounds, there is a lack of unified standards. Therefore, researchers should choose appropriate modeling and model evaluation methods based on actual needs to obtain the best experimental result.