Along with the development of the bio-psycho-social medical model, the impact of chronic psychological stress on diseases has increasingly drawn researchers" attention. Chronic psychological stress falls within the category of emotional etiology in traditional Chinese medicine. This paper systematically reviews the research progress of chronic psychological stress-related combination of disease and syndrome, analyzes the advantages and limitations of different models, and provides its own insights on the direction and improvement of future research on chronic psychological stress-related disease pattern models.