针刺干预调节慢性疼痛致抑郁的研究进展
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山东中医药大学

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中国博士后科学基金,国家自然科学基金项目(面上项目,重点项目,重大项目),山东省医药卫生科技项目,泰山学者工程专项经费资助,济南市市校融合发展战略工程项目,山东中医药大学中医药与脑 科学青年科研创新团队


Advances in Acupuncture Interventions on Depression Caused by Chronic Pain
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山东中医药大学

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China Postdoctoral Science Foundation, National Natural Science Foundation of China (face, key and major projects), Shandong Province Medical and Health Science and Technology Program, Taishan Scholars Project, Jinan City University Integration Development Strategy Project, Shandong University of Traditional Chinese Medicine, Chinese Medicine and Brain Science Youth Research and Innovation Team.

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    摘要:

    慢性疼痛不仅给患者带来生理痛苦,而且对患者的精神和心理产生巨大影响,严重者诱发抑郁症。已有研究表明,慢性疼痛和抑郁症在临床上常常同时出现,这提示两者可能存在相似的致病机制。针刺作为一种替代疗法,已被广泛应用于镇痛和抗抑郁的治疗,其作用机制与神经调节和内分泌调节密切相关。本文就慢性疼痛致抑郁可能的发病机制和针刺干预调节慢性疼痛致抑郁涉及的相关脑区和神经环路进行阐述,为慢性疼痛致抑郁的治疗提供新思路。

    Abstract:

    Chronic pain caused physical suffering and had a great impact on psychological aspect in patients. Severely, patients with chronic pain induced depressive disorder. Clinical studies have consistently shown that chronic pain and depression frequently co-occur, suggesting the possibility of shared pathogenic mechanisms underlying these conditions. Acupuncture, as an alternative therapy, has been widely used for analgesia and antidepressant treatment and acquired significant clinical efficacy. The mechanism of acupuncture in the treatment is related to neural and endocrine regulation. It was formulated that the mechanism of patients with chronic pain also were accompanied by depression and brain regions and neural circuits in acupuncture treatment. In short, this review provides a new sight for the treatment of depression caused by chronic pain.

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  • 收稿日期:2024-12-05
  • 最后修改日期:2025-05-26
  • 录用日期:2025-06-17
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