Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe form of pulmonary hypertension (PH) and is classified as the fourth major category of pulmonary arterial hypertension. It is primarily caused by chronic thrombosis, which leads to obstruction of blood flow in the pulmonary arteries, resulting in a sustained increase in pulmonary artery pressure. Due to the unclear pathogenesis of CTEPH, early diagnosis is challenging, treatment options are limited, and prognosis assessment is often inaccurate. In-depth research into these mechanisms not only helps in understanding the pathophysiological processes of CTEPH but also provides a theoretical basis for developing new therapeutic strategies. This paper mainly reviews the current methods of establishing CTEPH rat models and their advantages and disadvantages, offering researchers a reference for selecting and constructing CTEPH rat models.