Mitochondrial autophagy is a unique mechanism that selectively clears dysfunctional or excess mitochondria, closely related to Alzheimer"s disease (AD), characterized by aggregated neurotoxic proteins and dysfunctional mitochondria. In recent years, a large number of studies have confirmed that traditional Chinese medicine has significant therapeutic effects on Alzheimer"s disease. Its advantages of multi-target, multi pathway, and multi action have become an important component of Alzheimer"s disease. Chinese medicine formulas and monomeric active ingredients such as Jiannaoyizhi Fang, Danggui Shaoyao Tang, alkaloids, flavonoids, etc. can regulate mitochondrial autophagy related signaling pathways and targets, inhibit neuronal mitochondrial autophagy defects, and play a protective role in neurons. This review elaborates on the basic process of mitochondrial autophagy, related signaling pathways, molecular mechanisms in the pathogenesis of Alzheimer"s disease, and the latest research progress on the use of traditional Chinese medicine to improve AD by regulating mitochondrial autophagy. It is intended to provide ideas and references for future basic research and clinical treatment.