Research progress on animal models of low-back pain

doi:10. 3969 / j.issn.1005-4847. 2019. 03. 020

Home > Archive>Volume 27, Issue 3, 2019 >399-404. DOI:10. 3969 / j.issn.1005-4847. 2019. 03. 020

Research progress on animal models of low-back pain
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                        10. 3969 / j.issn.1005-4847. 2019. 03. 020
                    
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                        LI Hetong1LI Hetong
Department of Orthopedics, Affiliated Hospital of North China University of Science and Technology,Tangshan 063000, China.
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GOU Yu2GOU Yu
Graduate School of Hebei Medical University, Shijiazhuang 050017.
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TIAN Faming3TIAN Faming
Medical Research Center, North China University of Science and Technology, Tangshan 063210.
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ZHANG LiuZHANG Liu
1. Department of Orthopedics, Affiliated Hospital of North China University of Science and Technology,Tangshan 063000, China. 2.China Meitan General Hospital, Beijing 100028
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Affiliation:(1. Department of Orthopedics, Affiliated Hospital of North China University of Science and Technology,Tangshan 063000, China. 2. Graduate School of Hebei Medical University, Shijiazhuang 050017.3. Medical Research Center, North China University of Science and Technology, Tangshan 063210.4. China Meitan General Hospital, Beijing 100028)
Clc Number:Q95-33
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Abstract:

Low-back pain (LBP) is common and the cure rate is low. Its mechanism of action is incompletelyunderstood and may be related to degeneration of intervertebral disks, facet-joint injury, or inflammation of muscle fascia.Establishing an appropriate animal model can help to study and understand the pathogenesis of LBP, as well as explore itsprevention and treatment methods. This article summarizes the research progress of animal models which can be used to induce low-back pain.

Key words:low-back pain; lumbar disk herniation; lumbar facet arthritis; animal models

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Received:November 23,2018
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Online: July 09,2019
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