Methods and perspectives of application of gastric emptying detection techniques in laboratory animals

doi:10. 3969 / j.issn.1005-4847. 2019. 03. 022

Home > Archive>Volume 27, Issue 3, 2019 >410-414. DOI:10. 3969 / j.issn.1005-4847. 2019. 03. 022

Methods and perspectives of application of gastric emptying detection techniques in laboratory animals
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                        10. 3969 / j.issn.1005-4847. 2019. 03. 022
                    
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                        CHEN Xueyan1CHEN Xueyan
Department of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, China.
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WANG Lizhen3WANG Lizhen
Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063
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LIAO Zhonghua1LIAO Zhonghua
Department of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, China.
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LIU JuanLIU Juan
1. Department of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, China.2. Veterinary Science Engineering Center of Traditional Chinese Medicine Innovation Research Laboratory Chongqing, Chongqing 402460.
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Affiliation:(1. Department of Veterinary Medicine, Southwest University, Rongchang, Chongqing 402460, China.2. Veterinary Science Engineering Center of Traditional Chinese Medicine Innovation Research Laboratory Chongqing, Chongqing 402460. 3. Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063)
Clc Number:Q95-33
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Abstract:

Gastric emptying is important for measuring digestive tract function and plays an indispensable role inthe research on etiology, diagnosis and treatment of digestive diseases. In recent years, a series of detection methods hasbeen used to measure gastric emptying in humans: intubation, real-time ultrasound, radionuclide imaging and respiratorytesting. However, these method are relatively rarely used in laboratory animals. A method for evaluating the gastricemptyingability of laboratory animals correctly is very valuable for the study of the drug bioavailability and gastrointestinaldiseases. In this review, we discuss some of the methods commonly used for detection of gastric emptying in humans. We hope that we can provide some new ideas for detection of gastric emptying in animals.

Key words:gastric emptying; intubation; real-time ultrasound; radionuclide imaging; respiratory testing

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Received:November 16,2018
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Online: July 09,2019
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