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Home > Archive>Volume 27, Issue 4, 2019 >540-544. DOI:10. 3969 / j.issn.1005-4847. 2019. 04. 018
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Advances in research of the establishment of astrocyte models for treatment of spinal cord injury
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Affiliation:

(1. Gansu University of Traditional Chinese Medicine, Clinical College of Chinese Medicine, Lanzhou 730000, China.2. Gansu Provincial Hospital of TCM, Division 2 of the Spinal Column, Lanzhou 730050)

Clc Number:

Q95-33

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    Abstract:

    Spinal cord injury is an extremely complex and debilitating condition. Once spinal cord injury occurs, itis difficult to treat, and thus poses a great economic and social burden to both caregivers and healthcare resources. In recentyears, the establishment of rat spinal cord injury cell models has contributed to our understanding of the etiology andpathogenesis of spinal cord injury, in particular, the establishment of an astrocyte model has a profound significance for thetreatment of spinal cord injury. Studies have found that astrocytes, as target cells that can effectively promote tissueprotection and functional repair after spinal cord injury, directly or indirectly regulate spinal cord injury through blood-brainbarrier barrier. This paper reviews the recent studies on the preparation of astrocyte culture models to provide guidance forthe establishment of an Objective , quantitative, and simulative astrocyte model, and presents new ideas for the treatment of spinal cord injury.

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History
  • Received:January 13,2019
  • Online: September 04,2019
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