Establishment and evaluation of animal models of steroid-induced avascular necrosis of the femoral head

doi:10. 3969 / j.issn.1005-4847. 2019. 06. 017

Home > Archive>Volume 27, Issue 6, 2019 >799-804. DOI:10. 3969 / j.issn.1005-4847. 2019. 06. 017

Establishment and evaluation of animal models of steroid-induced avascular necrosis of the femoral head
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                        10. 3969 / j.issn.1005-4847. 2019. 06. 017
                    
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                        JIANG Wei1JIANG Wei
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.
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CAO LinzhongCAO Linzhong
1. Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. 2. Department of Spinal Surgery,Affiliated Hospital of Traditional Chinese Medicine University, Lanzhou 730020
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WU Mingjun1WU Mingjun
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.
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ZHANG Qi1ZHANG Qi
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China.
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Affiliation:(1. Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. 2. Department of Spinal Surgery,Affiliated Hospital of Traditional Chinese Medicine University, Lanzhou 730020)
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Abstract:

Owing to the widespread use of glucocorticoids, the incidence of steroid-induced avascular necrosis of the femoral head has increased year by year, but its pathogenesis and possible preventive measures are still unclear. To carry out in-depth research into its fundamental treatment, the establishment of an animal model of steroid-induced avascular necrosis of the femoral head will be the key to success. This paper reviews the research progress of modeling schemes, modeling animals and modeling standards.

Key words:Steroid-induced avascular necrosis; femoral head; animal model; evaluation

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Received:March 31,2019
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Online: January 07,2020
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