Progress of animal models of functional dyspepsia

doi:10. 3969 / j.issn.1005-4847. 2022. 02. 018

Home > Archive>Volume 30, Issue 2, 2022 >283-290. DOI:10. 3969 / j.issn.1005-4847. 2022. 02. 018

Progress of animal models of functional dyspepsia
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                        10. 3969 / j.issn.1005-4847. 2022. 02. 018
                    
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                        TAO Ruizhi1TAO Ruizhi
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China
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GU Renjun2GU Renjun
the Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210000
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XIA Yawen1XIA Yawen
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China
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HAN Hongkuan1HAN Hongkuan
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China
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LU Keqin1LU Keqin
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China
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LU Yin1LU Yin
Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China
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SUN Zhiguang2SUN Zhiguang
the Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210000
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Affiliation:1. Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210000, China. 2. the Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210000
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Abstract:

Functional dyspepsia (FD) is a common and recurring disease, which is difficult to treat so it becomes a refractory disease. Because of the unknown etiology of FD, the current modeling method used in animal research remain controversial. The lasting effect of animal models provides an important reference value for potential treatments of FD. However, no article has comprehensively summarized the lasting effect of existing animal models of FD. To provide a reliable reference for establishing an FD animal model, we classify each model as sustained type and temporary type based on its lasting effect.

Key words:functional dyspepsia; duration; animal model;methods of modeling

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Received:August 07,2021
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Online: June 27,2022
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