Behavioral measurements of visualization in rodent laboratory animals
CSTR:
Author:
Affiliation:

1. School of Basic Medicine Sciences, Peking University, Beijing 100191, China. 2. Department of Ophthalmology, Peking University Third Hospital, Beijing 100191

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    Rodents, as important experimental animals, are exceptionally well-suited for studies of peripheral visual field diseases because of their visual structure, and are therefore key to the development of drugs related to peripheral visual field diseases. Behavioral visual measurements, including qualitative as well as quantitative measures, have the positive characteristics of being concise, intuitive, non-invasive, reproducible and can compensate for the shortcomings of other visual measures. Qualitative measures for judging vision in rodents are simple and easy to perform, including the visual placing test, the visual cliff test, and looming visual stimuli. By contrast, quantitative measures such as a water maze and the visual water task can accurately measure the visual acuity of rodents. This review provides a reference for researchers using rodents as experimental animals for visual studies. In addition, it provides valuable information to select appropriate modeling method and behavioral tests according to the purpose of the study, which will help experimenters to improve the efficiency of animal vision detection by selecting appropriate tests.

    Reference
    Related
    Cited by
Get Citation
Related Videos

Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:February 28,2022
  • Revised:
  • Adopted:
  • Online: April 13,2023
  • Published:
Article QR Code