LYU Zhen
1. Key Lab of Aquatic Sports Training Monitoring and Intervention of General Administration of Sport of China, Jiangxi Normal University, Nanchang 330022, China. 2. Faculty of Physical Education, Jiangxi Normal University, Nanchan 330022GONG Zhigang
1. Key Lab of Aquatic Sports Training Monitoring and Intervention of General Administration of Sport of China, Jiangxi Normal University, Nanchang 330022, China. 2. Faculty of Physical Education, Jiangxi Normal University, Nanchan 3300221. Key Lab of Aquatic Sports Training Monitoring and Intervention of General Administration of Sport of China, Jiangxi Normal University, Nanchang 330022, China. 2. Faculty of Physical Education, Jiangxi Normal University, Nanchan 330022
Alcohol use disorder (AUD) is a neuropsychiatric disorder associated with behavior, psychosociology, and neurobiology. AUD is mainly diagnosed by judgment of behavioral criteria. The animal model of AUD is the basis of research. However, because of the complexity of AUD diagnosis, it is too difficult to establish an animal model that includes all characteristics of AUD. This review summarizes the relevant literature and divides the AUD model into forced administration and self-administration models. The advantages and disadvantages of alcohol-only drinking, alcohol gavage, an alcohol liquid diet, chronic intermittent ethanol exposure, two-bottle choice, and alcohol self-administration included in both models are described and compared. Additionally, the modeling method were explored by face, predictive, and construct validities to provide a theoretical basis and reference for researchers to choose AUD models.
