Advances in animal models of chemotherapy-induced peripheral neuropathy pain

doi:10. 3969 / j.issn.1005-4847. 2023. 03. 016

Home > Archive>Volume 31, Issue 3, 2023 >402-409. DOI:10. 3969 / j.issn.1005-4847. 2023. 03. 016

Advances in animal models of chemotherapy-induced peripheral neuropathy pain
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                        10. 3969 / j.issn.1005-4847. 2023. 03. 016
                    
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                        ZHANG Jun2,1ZHANG Jun
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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HUANG QinHUANG Qin
2. Department of Traditional Chinese Medicine, Chenjiaqiao Hospital, Shapingba District, Chongqing 401331
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XIAO Caizhi2,1XIAO Caizhi
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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XIA Dongqin2,1XIA Dongqin
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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CAO Jie2,1CAO Jie
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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TIAN Liya2,1TIAN Liya
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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LIU Shaoyong2,1LIU Shaoyong
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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WANG Wei2,1WANG Wei
1. Chongqing University Cancer Hospital, Chongqing 400030, China.
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Affiliation:1. Chongqing University Cancer Hospital, Chongqing 400030, China. 2. Department of Traditional Chinese Medicine, Chenjiaqiao Hospital, Shapingba District, Chongqing 401331
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Abstract:

Chemotherapy-induced peripheral neuropathy pain ( CIPNP) seriously affects quality of life and treatment of cancer patients, but its mechanism is unknown and there is no effective therapy. Animal models are important to study CIPNP and play an extremely important role in the study of pathogenesis and treatments. This article reviews the research status of CIPNP animal models in the previous 5 years, analyzes the advantages and disadvantages of several common modeling method , and introduces its pathogenesis. This review aims to provide a reference for researchers to choose more effective animal experimental models and new ideas for treatment.

Key words:animal model; chemotherapy-induced peripheral neuropathy pain; pathogenesis

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Received:September 03,2022
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Online: September 06,2023
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