Chemotherapy-induced peripheral neuropathy pain ( CIPNP) seriously affects quality of life and treatment of cancer patients, but its mechanism is unknown and there is no effective therapy. Animal models are important to study CIPNP and play an extremely important role in the study of pathogenesis and treatments. This article reviews the research status of CIPNP animal models in the previous 5 years, analyzes the advantages and disadvantages of several common modeling method , and introduces its pathogenesis. This review aims to provide a reference for researchers to choose more effective animal experimental models and new ideas for treatment.