Research progress on animal models of acute exacerbation of various respiratory diseases induced by compound factors
Author:
Affiliation:

1.Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province & Education Ministry of P.R. China, Henan University of Chinese Medicine, Zhengzhou 450046, China. 2. Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Zhengzhou 450046. 3. Academy of Chinese Medicine Sciences, Henan University of Chinese Medicine, Zhengzhou 450046

  • Article
  • | |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • | |
  • Comments
    Abstract:

    On the basis of the compound factors of clinical practice, some progress has been made in acute exacerbation models of respiratory diseases by the two-hit method. In this review, we summarize the current research on acute exacerbation models of pulmonary fibrosis, chronic obstructive pulmonary disease, and bronchial asthma established by compound factors. The characteristics and application scope of each model are compared and analyzed in terms of animal selection, model preparation method, and major histopathological changes, providing a reference for researchers to further improve and perfect the model or rationally select animal models.

    Reference
    Related
    Cited by
Get Citation
Related Videos

Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:May 25,2023
  • Online: December 29,2023
Article QR Code