Research progress on experimental models of idiopathic pulmonary fibrosis

doi:10. 3969 / j.issn.1005-4847. 2024. 01. 001

Home > Archive>Volume 32, Issue 01, 2024 >118-127. DOI:10. 3969 / j.issn.1005-4847. 2024. 01. 001

Research progress on experimental models of idiopathic pulmonary fibrosis
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                        10. 3969 / j.issn.1005-4847. 2024. 01. 001
                    
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                        LI Zhihui1LI Zhihui
1. Henan University of Chinese Medicine, Zhengzhou 450046, China
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YU Xueqing1,2YU Xueqing
1. Henan University of Chinese Medicine, Zhengzhou 450046, China; 2. the First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China
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YANG Shuguang2YANG Shuguang
2. the First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China
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YU Ningxia2YU Ningxia
2. the First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China
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ZANG Danyang1ZANG Danyang
1. Henan University of Chinese Medicine, Zhengzhou 450046, China
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Affiliation:1. Henan University of Chinese Medicine, Zhengzhou 450046, China; 2. the First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China
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Abstract:

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease. IPF incidence is increasing yearly with high mortality and poor prognoses. At present, IPF pathogenesis remains unclear, and its treatments are limited. The experimental model is important to further study IPF pathogenesis and explore effective preventive and therapeutic measures. In recent years, its modeling method have been continuously developed and optimized. This study summarizes the establishment method and research progress of IPF experimental models in recent years to provide ideas and references for preclinical research to select appropriate experimental models.

Key words:idiopathic pulmonary fibrosis; acute exacerbation; experimental model; traditional Chinese medicine model

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Received:September 07,2023
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Online: May 13,2024
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