Research progress in mouse models of sarcopenia

doi:10. 3969 / j.issn.1005-4847. 2024. 03. 015

Home > Archive>Volume 32, Issue 3, 2024 >404-410. DOI:10. 3969 / j.issn.1005-4847. 2024. 03. 015

Research progress in mouse models of sarcopenia
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                        10. 3969 / j.issn.1005-4847. 2024. 03. 015
                    
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Author:
                        JIA Xinao1,2JIA Xinao
1. Jilin Sino-Rok Institule of Animal Science, Changchun 130600, China; 2. College of Food Science and Engineering,Jilin Agricultural University, Changchun 130118, China
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TANG Yujiao1,3TANG Yujiao
1. Jilin Sino-Rok Institule of Animal Science, Changchun 130600, China; 3. College of Life Science, Changchun Sci-Tech University,Changchun 130600, China
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Affiliation:1. Jilin Sino-Rok Institule of Animal Science, Changchun 130600, China; 2. College of Food Science and Engineering,Jilin Agricultural University, Changchun 130118, China; 3. College of Life Science, Changchun Sci-Tech University,Changchun 130600, China
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Abstract:

We searched the literature related to sarcopenia to retrieve information on modeling method and modelevaluation schemes using sarcopenic mice. Here, we review the operation method, advantages and disadvantages, and application scopes of the four modeling method, including drug injection, aging, muscle atrophy, and transgenic mice, and summarize the method used to evaluate muscle function, muscle strength, and muscle endurance. We then compare their advantages and disadvantages, to provide a reference for subsequent research into sarcopenia.

Key words:sarcopenia; animal model; skeletal muscle aging; modeling method

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Received:July 14,2023
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Online: June 06,2024
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