Application of neurocircuit identification technology in traditional Chinese medicine brain science

doi:10. 3969 / j.issn.1005-4847. 2024. 08. 013

Home > Archive>Volume 32, Issue 8, 2024 >1059-1064. DOI:10. 3969 / j.issn.1005-4847. 2024. 08. 013

Application of neurocircuit identification technology in traditional Chinese medicine brain science
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                        10. 3969 / j.issn.1005-4847. 2024. 08. 013
                    
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                        CUI Yaru1,2,3,4CUI Yaru
1. Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine,Jinan 250355, China; 2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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GAO Qian1,2,3,4GAO Qian
1. Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine,Jinan 250355, China; 2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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LI Zifa2,3,4LI Zifa
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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HU Minghui2,3,4HU Minghui
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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ZHANG Hao2,3,4ZHANG Hao
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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GENG Xiwen2,3,4GENG Xiwen
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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WANG Xinyu2,3,4WANG Xinyu
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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WEI Sheng2,3,4WEI Sheng
2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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Affiliation:1. Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine,Jinan 250355, China; 2. Key Laboratory of Traditional Chinese Medicine Classical Theory,Ministry of Education, Shandong University of Traditional Chinese Medicine, Jinan 250355, China;3. High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China; 4. Chinese Medicine and Brain Science Interdisciplinary Research Center (CMBS), Shandong University of Traditional Chinese Medicine, Jinan 250355, China
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Abstract:

The neural circuit is the material carrier for the realization of brain function, consisting of a complex network of different neurons. Neural circuit identification technology tracks the structure and activity of specific neural circuits, to study their adequacy and necessity for brain function, which is crucial for understanding the pathogenesis of brain diseases. As a high-tech tool in the fields of neuroscience and brain science, neural circuit identification technology has been gradually introduced into basic traditional Chinese medicine ( TCM) research in recent years. This systematic review considers the principles of neural circuit identification technology and progress in its application in the field of TCM neuroscience. We note that future developments in this field should be based on the overall concept of TCM characteristics and the design of syndrome differentiation and treatment. Further research on the neural circuit mechanisms of diverse method of TCM in diseases will help to promote the deep integration of TCM and modern neuroscience.

Key words:neural circuit identification technology; traditional Chinese medicine brain science; application

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Received:December 05,2023
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Online: October 09,2024
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