Research progress in animal models of maternal separation and related mechanisms that affect learning and memory

doi:10. 3969 / j.issn.1005-4847. 2024. 09. 013

Home > Archive>Volume 32, Issue 9, 2024 >1215-1221. DOI:10. 3969 / j.issn.1005-4847. 2024. 09. 013

Research progress in animal models of maternal separation and related mechanisms that affect learning and memory
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                        10. 3969 / j.issn.1005-4847. 2024. 09. 013
                    
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                        LI Na1LI Na
1. School of Nursing, Southwest Medical University, Luzhou 646000, China
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SHE Guifang1SHE Guifang
1. School of Nursing, Southwest Medical University, Luzhou 646000, China
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WANG Yaxin1WANG Yaxin
1. School of Nursing, Southwest Medical University, Luzhou 646000, China
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LEI Qing1LEI Qing
1. School of Nursing, Southwest Medical University, Luzhou 646000, China
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SUN Hongyan1,2SUN Hongyan
1. School of Nursing, Southwest Medical University, Luzhou 646000, China; 2. Nursing Department of Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
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Affiliation:1. School of Nursing, Southwest Medical University, Luzhou 646000, China; 2. Nursing Department of Affiliated Hospital of Southwest Medical University, Luzhou 646000, China
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Abstract:

Maternal separation is a kind of social deprivation in early life that has been shown to impede the learning and memory abilities of rodents (mainly rats or mice) in adulthood. Animal models of mother-infant separation are commonly used to study the manifestations and mechanisms of learning and memory impairment. In this paper, an animal model of maternal-infant separation and related mechanisms of maternal-infant separation that affect offspring’s learning and memory are reviewed to provide a basis for subsequent research on maternal-infant separation.

Key words:maternal separation; learning and memory; animal model

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Received:December 08,2023
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Online: November 01,2024
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