Research progress in animal models of idiopathic pulmonary fibrosis
CSTR:
Author:
Affiliation:

1. College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China; 2. School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 611130, China; 3. College of Traditional Chinese Medicine, Hainan Medical University, Haikou 571199, China; 4. Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610040, China

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    As a chronic progressive lung disease with poor prognosis, the pathogenesis of idiopathic pulmonary fibrosis (IPF) has not yet been clarified, and its treatment is still being explored. Animal models are important tools for studying the pathogenesis and therapeutic effects of diseases. Based on the similarity between animal models and human of IPF in terms of disease phenotype, this paper will review the research progress of IPF animal models in terms of the fibrosis mechanism induced by drugs and environmental factors, histopathological alterations, fibrosis stage, modelling time, etc., and describe the advantages and disadvantages of different animal models, their characteristics and application profiles.

    Reference
    Related
    Cited by
Get Citation
Related Videos

Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:September 29,2024
  • Revised:
  • Adopted:
  • Online: July 08,2025
  • Published:
Article QR Code