Research progress of bronchoalveolar lavage in mice
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1.School of Basic Medical Science, Southwest Medical University;2.The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University

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Funded by Project of Sichuan Provincial Administration of Traditional Chinese Medicine (NO. 2021XYCZ006), Project of Southwest Medical University (NO. 2023XGZX008)

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    Abstract:

    Bronchoalveolar lavage is an important technique for studying respiratory diseases and has been widely used in disease research. Currently, the operation procedure of bronchoalveolar lavage in clinical patients has been gradually standardized, while mice, as one of the important model animals for studying lung diseases, still need a standard collection and testing procedure for bronchoalveolar lavage fluid for mice. An unstandardized procedure can hinder the promotion and application of this technique in research, and also affect the accuracy and reliability of experimental results. This paper presents a systematic summary of bronchoalveolar lavage methods for mice in domestic and international studies, with the aim of providing reference and guidance for researchers to apply and establish a standardized lavage procedure in the future.

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History
  • Received:May 18,2023
  • Revised:September 14,2023
  • Adopted:September 14,2023
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