Research Progress in experimental models of Idiopathic Pulmonary Fibrosis
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1.Henan University of Chinese Medicine;2.The First Affiliated Hospital of Henan University of CM

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    Abstract:

    Idiopathic pulmonary fibrosis ( IPF ) is a chronic, progressive interstitial lung disease. The incidence of IPF is increasing year by year, with high mortality and poor prognosis. At present, the pathogenesis of IPF is still unclear, and its treatment measures are limited. The experimental model is a key tool for further studying the pathogenesis of IPF and exploring effective prevention and treatment measures. In recent years, its modeling methods have been continuously developed and optimized. In view of this, this study summarizes the construction methods and research progress of IPF experimental models in recent years, in order to provide ideas and references for preclinical research to select appropriate experimental models.

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History
  • Received:September 07,2023
  • Revised:January 03,2024
  • Adopted:January 12,2024
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