Research progress of animal model construction of steroid- induced osteonecrosis of the femoral head
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1.Henan University of Traditional Chinese Medicine;2.Department of Orthopedics and Traumatology,the First Affiliated Hospital of Henan University of Chinese Medicine

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Special research project of TCM in Henan Province

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    Abstract:

    As a complex and refractory disease, the incidence of steroid-induced osteonecrosis of the femoral head (SONFH) is increasing year by year and showing a younger trend. A good animal model of disease can provide important support for the study of the pathogenesis of SONFH and the development of treatment methods. In this paper, the latest progress in the construction of SONFH animal models was summarized and analyzed from the aspects of animal selection, modeling methods and model evaluation by reviewing and sorting out the experimental studies related to SONFH animal models at home and abroad in recent years, so as to provide reference for the related research of SONFH.

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History
  • Received:January 22,2024
  • Revised:September 20,2024
  • Adopted:October 16,2024
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