Abstract:Objective:The characteristics of animal models of sequelae of pelvic inflammatory disease (SPID) were reviewed to provide a reference for standardizing the modeling process and improving the molding rate.Methods:The literature on animal models of SPID in the past 40 years was searched, and animal species, modeling methods, modeling cycles, modeling substances, positive control drugs, and evaluation indexes were summarized and analyzed.Results:A total of 243 literatures were included, most of which were induced by phenol paste method and microbial infection method to establish SPID model in rats. The modeling cycle was mainly 14-16 days, and the success of the model was mostly determined by pelvic tissue morphology observation and pathological HE staining. There are few researches on TCM disease combination model.Conclusion:The method of SPID animal model modeling lacks consistent criteria, so it is recommended to evaluate the changes of animal behavior, pelvic histomorphology and pathology. Secondly, TCM syndrome modeling lacks effective methods and evaluation standards, which need further research and development; Finally, the selection and use cycle of positive control drugs need to be further explored and perfected.