Progress in the study of animal models of atopic dermatitis in Chinese and Western medicine disease evidence
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1.Yunnan University of Chinese Medicine,Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine;2.Guangzhou Key Laboratory of Germ-free Animals and Microbiota Application;3.Key Laboratory of Viral Pathogenesis &4.Infection Prevention and Control (Jinan University), Ministry of Education;5.Yunnan University of Chinese Medicine, Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine,Guangzhou Key Laboratory of Germ-free Animals and Microbiota Application

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National Key R&D Programs of China (2022YFF0710701, 2022YFF0710702 ), Guangzhou Key Research and Development Program (202206010157),Guanzhou Joint Fund for Key Laboratory [grant number 202201020381]

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    Abstract:

    【】? In recent years, as the research on Chinese medicine in the treatment of immune system diseases has been gradually deepened, more and more Chinese medicines have shown good therapeutic effects on immune system diseases. Atopic dermatitis (AD) is an inflammatory disease characterized by type 2 immunity, and the research on its pathogenesis and therapeutic immunopharmaceuticals has been increasing, resulting in a variety of different types of animal models. The purpose of this paper is to review the existing animal models of AD and their immune-related characteristics, in the hope of providing appropriate references for the selection of future research models related to AD.

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History
  • Received:September 19,2024
  • Revised:April 16,2025
  • Adopted:April 30,2025
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