Analysis of the Application of Phenolic Adhesive Slurry Method in Gynecological Experimental Models
DOI:
CSTR:
Author:
Affiliation:

内蒙古医科大学

Clc Number:

Fund Project:

  • Article
  • |
  • Figures
  • |
  • Metrics
  • |
  • Reference
  • |
  • Related
  • |
  • Cited by
  • |
  • Materials
  • |
  • Comments
    Abstract:

    Phenol paste method is a widely used modeling technique in animal experimental models of gynecological diseases. This technique utilizes phenol paste as a chemical caustic agent, which is precisely injected into specific parts of the animal"s body to induce inflammatory responses, thereby simulating the pathological processes of human gynecological diseases. When constructing animal models of pelvic inflammatory disease, cervicitis, endometritis, salpingitis, and vaginitis, phenol paste is injected into the rat uterus as an adhesive agent, causing chemical burns to the endometrium. This burn leads to endometrial hyperemia, edema, inflammatory exudation, inflammatory adhesions, and blockage, resulting in chronic endometritis. The successful establishment of this model provides a crucial experimental basis for studying the pathological mechanisms and treatment methods of gynecological diseases. Additionally, phenol paste is also used to replicate animal models of gynecological diseases in traditional Chinese medicine, utilizing its corrosive and adhesive properties to create animal models based on the syndrome of dampness and blood stasis.

    Reference
    Related
    Cited by
Get Citation
Related Videos

Share
Article Metrics
  • Abstract:
  • PDF:
  • HTML:
  • Cited by:
History
  • Received:January 14,2025
  • Revised:April 22,2025
  • Adopted:April 30,2025
  • Online:
  • Published:
Article QR Code