Research progress in animal models of neurogenic bladder following spinal cord injury
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Hunan University of Chinese Medicine

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Funded by General Project of National Natural Science Foundation of China (82274666), Discipline Construction 'Leading the Charge with Open Competition' Project of Hunan University of Chinese Medicine (22JBZ013), Youth Project of Hunan Provincial Natural Science Foundation (2024JJ6340).

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    Abstract:

    Neurogenic bladder (NB) stands as one of the most challenging urinary system disorders, with spinal cord injury (SCI) being a primary etiological factor. Animal models serve as crucial instruments for investigating the pathogenesis, therapeutic strategies, and novel drug screening for NB subsequent to SCI. By reviewing and synthesizing recent literature on NB animal models after SCI from both domestic and international sources, this paper summarizes and analyzes the research advancements in such models, encompassing animal species, SCI segments, modeling techniques, and evaluation indicators. The aim is to offer insights and guidance for experimental research based on animal models of NB following SCI.

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History
  • Received:April 18,2025
  • Revised:July 04,2025
  • Adopted:September 05,2025
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