Animal models of hyperuricemia are widely used in hyperuricemia research, but there remains a lack of standardized preparation and evaluation protocols. Through a comprehensive review of domestic and international literature, this article summarizes and analyzes the current applications of hyperuricemia animal models. It systematically categorizes the selection criteria for commonly employed animal models in hyperuricemia studies, with particular focus on critical analysis of induced animal modeling methodologies. The findings aim to provide a reference framework for establishing reliable hyperuricemia animal models with enhanced pathophysiological relevance.