Laboratory Animal Monitoring Committee play a key role of controlling laboratory animal quality, in which there are datas needed for laboratory animal datawharehouse. In this paper, Laboratory Animal Monitoring Committe Office System is established in software MS Vbasic 6.0 and MS SQL 7.0, according to the process and speciality of Laboratory Animal Monitoring Committee, which is customized software and will improve the level of laboratory animal study in our country. For example, we intruduce whole process and some details of Programming GuangDong Laboratory Animal Monitoring Institute's Office process, which will be helpful to other Committe's quality control, process Stadardization and administration et al.