Progress of Animal Model of Human Chronic Myelogenous Leukemia
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R733 R587

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    Abstract:

    Three kinds of laboratory model mice in human chronic myelogenous leukemia are available, including xenotransplantation of CML cells into immunodeficient mice, bcr/abl retroviral bone marrow transduction and transplantation,bcr/abl transgenic mice. Recent studies in these different model systems have yielded important advances in our knowledge of the pathogenesis of human chronic myelogenous leukemia.

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  • Received:
  • Revised:April 06,2004
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