Graves’ disease ( GD) is a common organ-specific autoimmune disease, and its pathogenesis and etiology are not very clear. Currently, it is generally believed that the pathogenesis of GD is related to genetic, immunological and environmental factors. In recent years, a variety of immune cells have been found to be involved in the pathogenesis of GD, which provides a new idea for the diagnosis and treatment of GD. Various studies have shown that abnormal expression of helper T cells, regulatory T and B cells as well as abnormal secretion of cytokines, are related to the pathogenesis of GD. Therefore, this article reviews the role of helper T cells, regulatory T cells and regulatory B cells in GD