Abstract:Allergic asthma is a chronic airway inflammatory disease caused by type 2 inflammatory response- mediated hypersensitivity. At present, no animal model of asthma that completely recapitulates the occurrence and development of allergic asthma in humans is available. Therefore, it is particularly important to establish a relatively complete and stable animal model of allergic asthma that conforms to the pathological manifestations of patients. This review briefly analyzes the strain selection, modeling method, and model evaluation indicators of allergic asthma model rats in the past 5 years.