The purpose of this paper is to introduce the design, function, manipulation and applications of a computer software for management of laboratory animal reproduction. The system may be used for the data collection and statistical analysis in the process of laboratory animal reproduction and sell, including the recording and browsing of weekly sell and cost forms, the making of report forms of weekly animal amount in stock, the producing and printing of monthly, quarterly and annual report forms, the calculation of cost and the making of chart. The system meets the needs in the management of reproduction and sell in breeding facilities and supply a scientific and convenient method for the management of laboratory animals.