Objective To evaluate the reproduction and growth of the Kunming(KM) mice in Lanzhou Institute of Biological Products(LIBP), as a part of the study on KM mice's biological features standardization in People's Republic of China.Methods 170 pregnant female mice were chosen from the workshop's population and the growth of the baby mice was evaluated by measuring the litter weight of 3, 7, 10, 14 days and the body weight of 3, 4, 5, 6, 8, 10, 12, 14*!weeks after birth.140 pairs of mature mice were used. Of which 136 pairs were mated within 70-75 days. The reproduction of these mice were evaluated by measuring the producing rate in 30 days after mating, the average litter number per birth, the survival rate of weaning and the time of between births.Results The average weight of newborn litter is 20g; by 14th day, the average weight of litter is 67.4g. By 10th week, the male mice weigh 39.22g,showing body-mature, and the female mice weigh 32.45g, above 90% of body-mature. The producing rate within 30 days after mating is 81.6%. The producing average of 1-5 births is above 10, the producing average of 6-10 births is about 7. The average weaning rate is 84%.Conclusion The results above could provide a reliable data for the standardization of KM in China.