Parkinson's disease(PD) is a common ailment in the elderly, showing neurochemical abnormalities and dyskinesia. In order to deeply research the cause and treatment of PD, different animal models have been established. In this article the authors described the development of several non-prinmate and rodent models with Parkinson's disease and L-DOPA induced dyskinesia. Because of their different traits, appropriate animal models should be chosen according to experiments.