Objective To study teratogenic effects of Scutellaria baicalensis Georgi on embryos of SD rats. Method Gravid femals SD rats were randomly divided into five groups, then weighed and tagged. They were administered from 7 through 16 days of their gestation. The rats were weighed and killed on the 20th day of the gestation, embryonic developmental parameters and fetal developmental parameters were analysed, external and skeletal anomalies were examined. Results No significant differences were observed between the Scutellaria baicalensis Georgi dosage groups and the negative control group in body weight gain in pregnant rats. And there were no reduction of number of survivals at birth, no increment of incidence of stillbirth, no decrement of mean body weight, body length and tail length, no retardation of skeletal development, no increment of incidence of external and skeletal anomalies in the fetuses of experimental groups. Conclusion Scutellaria baicalensis Georgi has no maternal toxicity, embryonic and developmental toxicity and teratogenicity under the experimental conditions.