杜仲对兔骨折愈合影响的光镜观察实验研究
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R274.1


A light Microscopic Observation on the Effects of Cortex Eucommia on Fracture Healing in Rabbits
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    摘要:

    目的光镜下研究单味药杜仲促进骨折愈合的机理。方法手术造成兔胫骨中下段骨缺损模型45只,随机分成治疗组(n=23只)和空白对照组(n=22只),分别给予杜仲浓缩液及等量生理盐水灌胃,在造模后7、17、27、37、47d分别对骨断端进行光镜观察,对其半计量数据进行统计学分析。结果治疗组组织学光镜观察评分分别为4.6±1.14,8.0±1.58,12.6±0.55,14.6±1.34,16.0±1.22,与同期对照组相比P<0.05,差异有显著性。光镜观察发现实验组比对照组较早出现修复反应。结论杜仲浓缩液可促进骨折愈合。

    Abstract:

    Objective To investigate the effect of Cortex Eucommiae on the fractures healing process. Methods Tibia fracture models were created in 45 rabbits. The animals were divided into experiment (n=23) and control groups (n=22). The experimental rabbits were intragastrically administered with Cortex Eucommiae and the control animals received the same amount of physiological saline. The fracture ends were taken for light microscopic examination on days 7, 17, 27, 37 and 47 of the experiment and the histopathological data were semi quantitatively analyzed. Results The light microscopic observation demonstrated that the repairing responses occurred earlier in the experimental group than that in control group. Conclusion The concentrated extracts of Cortex Eucommiae taken orally accelerates the healing process of fracture in rabbits.

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崔永锋,张永斌,李刚,张安琪,闫红伟.杜仲对兔骨折愈合影响的光镜观察实验研究[J].中国比较医学杂志,2005,(3):154~156.

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  • 最后修改日期:2004-06-13
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