This paper reviewed the mechanisms of improving effects of Paliax ginseng(PG) to several stroke models.PG could improve the disorder behaviors of learning and momeory induced in different stroke models,the mechanisms related to produce a marked effect on modulating the function of cholinergic system;antiperoxidation of free radical;inhibit the apoptosis of neurocyte;protecting the function of chondrisome;relieving the neurotoxicity of excitatory amino acid; regulating the activity of NO.