分子遗传标记技术在兔遗传多样性分析中的应用
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作者简介:

申幸娇(1987-)女,硕士研究生,E-mail:xjshen816@163.com。

基金项目:

重大疾病动物模型和实验动物资源的标准化及评价体系的建立(2011BAI15B00)。


Application of the Technology of Molecular Markers on the Analysis of Genetic Diversity of Rabbits
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    摘要:

    实验兔是重要的实验动物之一,在医药领域发挥重要作用。各种分子遗传标记的出现为实验兔系统发育、种群遗传结构分析以及质量控制等各个领域提供了更为简便、可靠的研究手段。但目前,国内实验兔遗传质量不稳定,遗传背景不明确,严重制约着实验兔的应用。本文对各种分子标记在兔遗传多样性中的应用进行综述,以为实验兔遗传检测方法的建立提供帮助。

    Abstract:

    Experimental rabbits,one of the most important experimental animals,played an imptant role in medical field. All kinds of genetic markers methods provided more simple, reliable research methods for system development, population genetic structure and quality control, and other fields. However, the application of domestic experimental rabbits is restricted because of their unstalbe quality and unclear genetic background. In this paper, applications of the technology of molecular markers on the analysis of genetic diversity of rabbits are summarized, aimed at providing some help to genetic testing of experimental rabbits.

    参考文献
    [1] 商海涛,魏泓,岳秉飞,徐平.应用微卫星DNA 标记对Wistar 和SD 大鼠封闭群的遗传学研究[J].分子细胞生物学报,2008,41(1):28-33.
    [2] 冯洁,谢建云,胡建华,等.上海地区实验用兔线粒体DNA-RFLP分析[J].上海交通大学学报.2007,25(6):547-550.
    [3] 夏圣荣,冯凯,吴添文,等.5 个家兔群体FGF5 基因部分外显子1 的遗传多样性分析[J].草食家畜.2010.(4):22-25.
    [4] 邝良德,谢晓红,黄邓萍,等.4个家兔品种MHC-DQA基因外显子2MboⅡ酶切多态性分析[J].中国畜牧兽医.2011,38(4):137-139.
    [5] John Welsh, Michael McClelland.Fingerprinting genomes using PCR with arbitrary primers [J].Nucleic Acids Research,0,8(24):7213-7218.
    [6] John G K Williams,Anne R Kubelik, Kenneth J Livak, et al.DNA polymorphisms amplified by arbitrary primers are useful asgenetic markers [J].Nucleic Acids Research,0,8(22):6531-6535.
    [7] Ramessur AD, Ranghoo-Sanmukhiya VM.RAPD marker-assisted identification of genetic diversity among mango (Mangifera indica) varieties in Mauritius[J].International Journal of Agriculture and Biology.2011;13(2):167-173.
    [8] Bochra L, Nejia Z, Myriam L, Karima K, Abdelwahed G, Abdelaziz M.RAPD-based assessment of genetic diversity among annual caraway (Carum carvi) populations[J].EurAsian Journal of BioSciences.2011;5:37-47.
    [9] Wang BY, Shi L, Ruan ZY, Deng J.Genetic diversity and differentiation in Dalbergia sissoo (Fabaceae) as revealed by RAPD[J].Genetics and Molecular Research.2011;10(1):114-120.
    [10] Saeed A, Ahsan I, Sehar N, Nisar A.Genetic diversity studies of coarse and fine rice using RAPD markers[J].Frontiers of Agriculture in China.2011;5(2):129-134.
    [11] 杨丽萍,张玉笙,吕连山,等.不同品系家兔的RAPD 遗传分析[J].中国养兔杂志,2000,(3):15-18.
    [12] 陈民利,赵伟春,应华忠,等.WHBE 兔遗传特异性的RAPD 的分析[J].浙江大学学报(农业与生命科版).5,1(4):493-498.
    [13] 赵立虎,谢夏阳,赵丹凤.RAPD分子标记技术用于实验兔品系鉴定的初探[J].上海交通大学学报.7,2(25):66-70.
    [14] 任克良,李燕平.獭兔RAPD 标记与部分繁殖性能相关的研究[J].中国草食动物 7,7(6):38-39.
    [15] 蔡月琴,屠珏,余佳,等.RAPD 标记技术用于WHBE 兔近交系培育中的遗传分析[J].中国实验动物学报, 9,7 (5):326-329.
    [16] 李润枝,张娟.SSR技术在遗传多样性研究中的应用[J].安徽农业科学, 0,8 (20):10492-10494
    [17] Joongho Shin,Azadeh Azarbayejani,Ziqian Yuan,et al.A mutation within the 3''untranslated region of the EGFR gene contributes to EGFR overexpression in microsatellite unstable(MSI)colon cancer(CRC)that results from increased mRNA stability [J].Journal of the American College of Surgeons, 8,7(3):S102-S103.
    [18] Abeeha Z Gardezi,Yalda Z Ziaei,Sahar M Marashi. Microsatellite polymorphism of the human leptin gene and risk of obesity[J]. Journal of Critical Care,8,3(3):440-444.
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申幸娇,岳秉飞.分子遗传标记技术在兔遗传多样性分析中的应用[J].中国比较医学杂志,2012,(9):72~76.

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