目的对本单位封闭群NIH小鼠发生的皮下肿瘤进行诊断。方法统计发病率、发病体重、分娩胎次等信息,并切除肿瘤组织制作病理切片。结果该肿瘤发病率为1.32%,病理切片诊断为纤维腺瘤。结论本单位饲养繁殖的NIH小鼠发生皮下肿瘤诊断为纤维腺瘤,其发病原因需进一步研究探索。
ObjectiveTo diagnose the subcutaneous tumors in the NIH mice in bred in the laboratory animal center in our company.MethodsTo statistically analyze the morbidity, body weight and parturition times of the NIH mice bred in our animal center. Tumor samples were taken for pathological examination. ResultsOne hundred and fifty-four subcutaneous tumors were found among 11711 mice. The pathological diagnosis of the subcutaneous tumors was fibroadenoma, and the incidence rate was 1.32%. ConclusionsThe tumor of NIH mice bred in our company laboratory animal center is fibroadenoma. The etiology of this tumor needs to be further investigated.
潘若文,马力,张鹏飞,翟三姗,原增泉. NIH小鼠纤维腺瘤流行病学及病理学诊断[J].中国比较医学杂志,2012,(12):23~24.
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