ObjectiveTo study the influence of enriched environment on the growth and behavior of guinea pigs. MethodsThe breeding environment of guinea pigs was enriched by adding tube-shaped mould and trapezium-shaped mould. Thirty-two healthy guinea pigs were randomly divided into 4 groups, with 8 animals in each group:normal control, tube mould, trapezium mould, tube and trapezium mould groups. The body weight of guinea pigs was recorded every week for 4 weeks, and the behavior changes of the guinea pigs were observed. ResultsThe growth of guinea pigs bred in the enriched environment was better than that of the control animals, and the tube mould showed better effect than the trapezium mould. ConclusionsEnriched environment with moulds is beneficial for guinea pig breeding. The tube-shaped mould is more close to a natural cave, may be beneficial for the guinea pigs to hide, and provides for them a better growing and living environment.