Abstract:Objective To report the results of medicated bath with ivermectin for eradication of external parasites in mice.Methods Nearly 800 genetically engineered mice which are self-used were treated with ivermectin medicated bath in concentration of 1% (L/L) to eradicate external parasites. Each mouse swims at least 1 minute, including immersing the head into solution for 3-4 times with a colander. Manual auxiliary medicated bath was needed for less than 10-day ones.All cages and materials were changed after the medicated bath, and environmental disinfection was performed at the same time. Medicated bath was used only once.Results Mortality rate of the mice was about 2%. The mice were followed-up for 18 months, and no reinfection with external parasites was observed. The mice were healthy and reproduction was normal.Conclusions Medicated bath with ivermectin is effective and feasible for eradication of external parasites in laboratory mice.